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International ISSX Meeting

Connect with Labcorp at International ISSX Meeting

Sep 21 – Sep 24, 2025 | Chicago, IL, USA

With more than 80 years of toxicology experience, Labcorp is focused on delivering the answers you need to move your program to the next milestone. Our global capacity, flexible scheduling and rapid study initiation creates a streamlined approach to nonclinical services, which means successful design and execution of your program across discovery, safety pharmacology, toxicology, pathology, bioanalysis, radiopharmaceuticals, drug metabolism and pharmacokinetics.

Propel your development program with our comprehensive DMPK solutions
 

In vitro metabolism

In vivo metabolism

MetID

Pharmacometrics

 

Meet our team at ISSX 2025

Booth #109:

Our commercial and scientific team members will be on-site to provide comprehensive and strategic insights to help reduce risk and move your program more efficiently across critical milestones. 

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Posters

Session Date & Time Title

Abstract #

Monday, September 22 
12:00 PM - 3:00 PM 
NAMS in DMPK: Case Studies and Context of Use Applications P45
Monday, September 23 
12:30 PM - 2:30 PM
Development and Implementation of a Mouse Bile-duct Cannulated Model for use in DMPK Studies 120
Tuesday, September 23 
12:30 PM - 2:30 PM 
Increasing Animal Reuse: Novel Approaches to Achieving a 3RS Reduction of all Naïve Animal Species used Across Nonclinical Studies P54

 

Presentation

Session Date & Time

Title

Wednesday, September 24
12:45 PM - 12:55 PM
Strategic Advantage: Leveraging NAMs to De-Risk and Accelerate Drug Development

A review of the global regulatory and governmental drivers, challenges and opportunities to embrace, utilize, and adopt New Approach Methodologies (NAMs). There will be a particular emphasis on US-based activities, including interpretation and commentary on the FDA roadmap announcement. The talk will provide some insight and discussion around where Labcorp see opportunities for accelerating the use of NAMs to support drug development and chemical evaluation in the near, medium and longer terms from the subsequent symposium speakers. Finally, the presentation will highlight:

  • DMPK being a cornerstone discipline utilizing NAMs
  • Early use of NAMs based DMPK data in decision making is hugely beneficial to de-risking compound development
  • Further integration of modelling, in silico, AI, and wider human based MPS and organoid tools in DMPK will be employed in the future to provide greater insights into translatability of NAMs

Regulatory landscapes, and incentives to use NAMs, will evolve as the science matures, building confidence in translation and predictivity of these new approaches.

Learn more at labcorp.com/biopharma/nonclinical.

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